VIME mission

Metabolomics, the unbiased profiling of all small molecules in biological samples, has developed into a core technology for functional genomics, biobased economy and personalized medicine in the last decade. Recently, ecological metabolomics has emerged in ecosystem research and metagenomic studies. The quality of state-of-the-art metabolomics technology depends on the quality of the preparation workflows, the quality of metabolite libraries and workflows for structural elucidation of novel structures.

Because of the diversity of the metabolomes from organisms in functional and biomedical studies as well as the complexity of exo-metabolomes in environmental samples from marine, fresh water and terrestrial ecosystems an interdisciplinary approach is necessary to tackle this problem. Internationally recognized labs at the University of Vienna distributed over three faculties for Chemistry, Geosciences and Life Sciences consolidate their specific and complementary metabolomics platforms and application fields to build a Vienna Metabolomics Center.

VIME in space - MOMEDOS


How do microbes in cosmic dust adapt to outer space conditions?

VIME collaborates with Dr. Tetyana Milojevic from the Department of Biophysical Chemistry to investigate the molecular mechanisms of microbial adaptation to outer space conditions such as cold and radiation. The project is funded by the FFG and will investigate samples from the TANPOPO mission.

Stardust Dust Collector with aerogel (Source:



Researching the effects of ageing and lifestyle activities at cellular and molecular levels

In a close collaboration with the coordinator of the research platform Active Aging Karl-Heinz Wagner the Vienna Metabolomics Center will contribute metabolomic profiles of large cohorts of elderly participants.


VIME works on Alzheimer diagnostics


Early and accurate Alzheimer diagnostics allow patients to delay the deseases' effects and preserve daily functioning for some time.

VIME collaborates with Maria Zellner, an expert on Alzheimer Disease and Jürgen König on early and rapid Alzheimer diagnostics. Dr. Maria Zellner coordinates LOAD, a Marie Curie Action for Industry-Academia Partnerships and Pathways (IAPP) on the development of a late-onset- Alzheimer’s disease profile for accurate diagnosis and identification of potential therapeutic approaches.

Neurofibrillary tangles in the Hippocampus of an Alzheimer patient. Source: Patho -



The human gut system hosts a vast amount of different microorganisms who influence metabolism and health. This is also reflected in metabolomic profiles.

The Vienna Metabolomics Center is part of the expert consortium of the recently established Austrian Microbiome Initiative (AMICI) headed by Christoph Steininger. In the close collaboration of VIME and AMICI potential fields of collaboration will be explored.


VIME goes proteomics: Exo-proteomics of marine samples


Dissolved organic material in ocean water - what ist it composed of, and what role do microorganisms play in structuring this dissolved matter?

Roberta Hansman received a four-year Else Richter grant from the Austrian Science Fund (FWF) to analyze dissolved proteins found in seawater. Proteins comprise about 50% of all living organisms, including the millions of microbes present in every liter of seawater, and thus become a major component of the dissolved organic material found in the ocean. This work will identify and quantify proteins dissolved in seawater in combination with analysis of the exo-metabolome in order to gain insight into what organic material in the ocean is composed of and what role microorganisms play in structuring dissolved organic matter composition. The project will be conducted within the Vienna Metabolomics Center. Roberta Hansman is member of the Microbial Oceanography lab headed by Gerhard Herndl.


VIME - Vienna Metabolomics Center